
Case Western Reserve University Awarded $7.3M for Eye Research

CLEVELAND — Case Western Reserve University School of Medicine has been awarded a five-year, $7.3 million grant from the National Institutes of Health to identify new technology, methods and models to study the impact of inflammation and pain on the surface of the eye.
“The cornea is the most densely innervated tissue in the body, yet we have a poor understanding of how structural and functional integrity is maintained at the eye surface,” said Michael Jenkins, the Dr. Donald and Ruth Weber Goodman professor of Innovative Cardiovascular Research at the School of Medicine, and principal investigator on the project.
“Understanding neural control at the eye’s surface is critical to understand many diseases, including dry-eye disease, diabetes and more,” he said. “This will also help us better understand problems like corneal neuropathic pain.”
Jenkins said the research will involve a multidisciplinary team from CWRU and Cleveland Clinic with expertise in such areas as advanced 3D microscopy, neuroscience, pain, immunology, spatial statistics and machine/deep learning, among other areas.
The team will also investigate eye surface control under different inflammatory and pain conditions such as evaporative dry-eye disease, diabetes and bacterial keratitis to better understand how treatment options affect the eye surface control system.
In The News
Health
Voting
Research
WASHINGTON — An experimental vaccine against Marburg virus, a member of the Ebola virus family that causes death in a... Read More
WASHINGTON — An experimental vaccine against Marburg virus, a member of the Ebola virus family that causes death in a large proportion of infected individuals, proved safe and induced an immune response in a small, first-in-human clinical trial. The findings of the researchers at the National... Read More
WASHINGTON — A probiotic may be effective in cleansing the body of staph-related super infections, according to a new study... Read More
WASHINGTON — A probiotic may be effective in cleansing the body of staph-related super infections, according to a new study from the National Institute of Allergy and Infectious Diseases. Though they say more research is needed, a press release on the institute’s website stated that their... Read More
WASHINGTON — Scientists with the National Cancer Institute’s Center for Cancer Research have come up with a new way to... Read More
WASHINGTON — Scientists with the National Cancer Institute’s Center for Cancer Research have come up with a new way to get life-saving drugs directly into cancer cells, an advance they say will enable more effective treatments for cancer with fewer side effects. The research was originally... Read More
WASHINGTON — The Agriculture Department’s Animal and Plant Inspection Service is developing new tests and tools to identify and track... Read More
WASHINGTON — The Agriculture Department’s Animal and Plant Inspection Service is developing new tests and tools to identify and track the coronavirus and its variants in wild and domestic animals. The initiative, part of a $300 million provision in the American Rescue Plan Act, is being... Read More
WASHINGTON — The U.S. Department of Agriculture is investing $9.5 million to support the scale-up of sustainable bioproduct manufacturing in... Read More
WASHINGTON — The U.S. Department of Agriculture is investing $9.5 million to support the scale-up of sustainable bioproduct manufacturing in the United States. The three projects being funded through the department’s National Institute of Food and Agriculture included two university-based initiatives and one effort being undertaken... Read More
WASHINGTON — The Energy Department is making $740 million in bipartisan infrastructure law funding available to dramatically reduce the cost... Read More
WASHINGTON — The Energy Department is making $740 million in bipartisan infrastructure law funding available to dramatically reduce the cost of clean-energy technologies. According to department officials, who announced the funding last week, the infusion of money is crucial to the administration’s effort to accelerate the... Read More